PEGS Boston 2026: Design Is the Easy Part Now
Five days at PEGS Boston. The design question is mostly answered. The hard problems have moved to CMC tolerance and immune acceptance, and the field knows it.
// ALL.SEQUENCES
All posts
Every entry, chronologically. Hover a row — the helix lights up; an antibody binds.
Nanobodies From a Laptop, BCRs From a Model, and a Mutation-Agnostic Bet
Three signals this month, all pointing at the same thing: antibody discovery is becoming a computational discipline first and a wet-lab one second.
Nanobodies in silico, rabbits in wet lab, and a mutation-agnostic antibody that skips the JAK2 debate
Antibody discovery is splitting into two cultures. One trusts the model. The other trusts the rabbit. Both had a good month.
VHH Humanization Is Mostly a Search Problem, Not a Grafting Problem
Everyone frames nanobody humanization as CDR grafting. It's not. It's a search problem with a brutal fitness landscape.
Data Governance in Pharma: Notes from the Pistoia Alliance Benelux Forum #5
A speaker-by-speaker recap of the European Life Science Informatics Forum Benelux #5 at GSK Wavre: data governance, FAIR, and agentic AI in drug discovery.
Untar/Unzip Multiple Files in One Command
A quick tip showing how to untar or unzip multiple archive files in one go using find and tar.
Linking Sublime as IDE
Setting up Sublime Text 3 as a default IDE with Jekyll support and Markdown editing.