RadTech — Notes from inside antibody discovery × AI https://radtech.nl Field notes from inside therapeutic antibody discovery and AI: weekly posts on what the literature actually says, what the platforms get wrong, and what to build next. en Sat, 30 May 2026 20:13:50 GMT PEGS Boston 2026: Design Is the Easy Part Now https://radtech.nl/blog/2026-05-20-pegs-boston-2026-design-is-the-easy-part-now/ https://radtech.nl/blog/2026-05-20-pegs-boston-2026-design-is-the-easy-part-now/ Wed, 20 May 2026 00:00:00 GMT Five days at PEGS Boston. The design question is mostly answered. The hard problems have moved to CMC tolerance and immune acceptance, and the field knows it. Nanobodies From a Laptop, BCRs From a Model, and a Mutation-Agnostic Bet https://radtech.nl/blog/2026-04-26-nanobodies-from-a-laptop-bcrs-from-a-model-and-a-mutation-agnostic-bet/ https://radtech.nl/blog/2026-04-26-nanobodies-from-a-laptop-bcrs-from-a-model-and-a-mutation-agnostic-bet/ Sun, 26 Apr 2026 00:00:00 GMT Three signals this month, all pointing at the same thing: antibody discovery is becoming a computational discipline first and a wet-lab one second. Nanobodies in silico, rabbits in wet lab, and a mutation-agnostic antibody that skips the JAK2 debate https://radtech.nl/blog/2026-04-24-nanobodies-in-silico-rabbits-in-wet-lab-and-a-mutation-agnostic/ https://radtech.nl/blog/2026-04-24-nanobodies-in-silico-rabbits-in-wet-lab-and-a-mutation-agnostic/ Fri, 24 Apr 2026 00:00:00 GMT Antibody discovery is splitting into two cultures. One trusts the model. The other trusts the rabbit. Both had a good month. VHH Humanization Is Mostly a Search Problem, Not a Grafting Problem https://radtech.nl/blog/2026-04-24-vhh-humanization-is-mostly-a-search-problem-not-a-grafting-p/ https://radtech.nl/blog/2026-04-24-vhh-humanization-is-mostly-a-search-problem-not-a-grafting-p/ Fri, 24 Apr 2026 00:00:00 GMT Everyone frames nanobody humanization as CDR grafting. It's not. It's a search problem with a brutal fitness landscape. Data Governance in Pharma: Notes from the Pistoia Alliance Benelux Forum #5 https://radtech.nl/blog/2026-04-21-data-governance-in-pharma-pistoia-benelux/ https://radtech.nl/blog/2026-04-21-data-governance-in-pharma-pistoia-benelux/ Tue, 21 Apr 2026 10:00:00 GMT A speaker-by-speaker recap of the European Life Science Informatics Forum Benelux #5 at GSK Wavre: data governance, FAIR, and agentic AI in drug discovery. Untar/Unzip Multiple Files in One Command https://radtech.nl/blog/2015-08-05-untar-unzip-multiple-files/ https://radtech.nl/blog/2015-08-05-untar-unzip-multiple-files/ Wed, 05 Aug 2015 00:00:00 GMT A quick tip showing how to untar or unzip multiple archive files in one go using find and tar. Linking Sublime as IDE https://radtech.nl/blog/2015-07-31-linking-sublime-as-ide/ https://radtech.nl/blog/2015-07-31-linking-sublime-as-ide/ Fri, 31 Jul 2015 00:00:00 GMT Setting up Sublime Text 3 as a default IDE with Jekyll support and Markdown editing. Posts https://radtech.nl/blog/-index/ https://radtech.nl/blog/-index/ Sat, 30 May 2026 20:13:50 GMT